Chinese Name: Ju hua
Medical Name: Flos Chrysanthemi
Latin Name: Chrysanthemum morifolium
Taste: Pungent, bitter and sweet in flavour
Quotes from Chinese historical sources
THE HERBAL CLASSIC OF SHEN NONG: "It is indicated for dizziness due to wind, swellings and pains, glaucoma and dacryorrhea."
OPINIONS ON THE PROPERTIES OF HERBS: "It treats pathogenic wind-heat in the head and eyes, dizziness and pains in the chest, disperses urticaria from the body and promotes the circulation."
SIMPLIFIED MATERIA MEDICA: "It calms the liver, soothes the lungs, expels wind pathogens from the upper part of the body, treats the eyes, dispels wind, replenishes yin and nourishes the kidneys."
Adv Exp Med Biol 1998;439:191-225
Recent advances in the discovery and development of flavonoids and their analogues as antitumor and anti-HIV agents.
Wang HK, Xia Y, Yang ZY, Natschke SL, Lee KH.
Natural Products Laboratory, School of Pharmacy University of North Carolina, Chapel Hill 27599, USA.
In our laboratory, acacetin-7-O-beta-D-galactopyranoside from Chrysanthemum morifolium and chrysin (102), as well as apigenin-7-O-beta-D-glucopyranoside (130), from Kummerowia striata, have been found to exhibit anti-HIV activity. In other studies, some flavonoids and related compounds have been investigated as inhibitors of HIV-1 reverse transcriptase, protease, and integrase. The isolation and structural modification of such plant-derived active principles provide a continuing source of potential antitumor and anti-HIV agents.
J Nat Prod 1994 Jan;57(1):42-51
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.
Hu CQ, Chen K, Shi Q, Kilkuskie RE, Cheng YC, Lee KH.
Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill 27599.
An active anti-HIV principle, acacetin-7-O-beta-D-galactopyranoside, has been isolated from Chrysanthemum morifolium. Seven additional flavonoids isolated from this plant, 13 known related flavonoids, and 14 synthetic flavonoids were also evaluated as inhibitors of HIV replication in H9 cells.
Zhongguo Zhong Xi Yi Jie He Za Zhi 1993 Mar;13(3):147-9, 132
A prospective clinical study on reversion of 200 precancerous patients with hua-sheng-ping[Article in Chinese]
Second Clinical Medical College, Xi'an Medical University.
200 precancerous patients were treated by the drug Hua-sheng-ping. The total effective rate was 95.5% compared with a control group rate of 57%. The constituents include Chrysanthemum morifolium, Glycyrrhiza uralensis, Panax notoginseng. It has been proved to be an effective prescription for precancerous lesions.
Chem Pharm Bull (Tokyo) 1991 Dec;39(12):3346-7
Studies on aldose reductase inhibitors from natural products. IV. Constituents and aldose reductase inhibitory effect of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas.
Terashima S, Shimizu M, Horie S, Morita N.
Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan.
Extracts of Chrysanthemum morifolium, Bixa orellana and Ipomoea batatas were found to have potent inhibitory activity towards lens aldose reductase (AR). Ellagic acid was isolated from C. morifolium and I. batatas, isoscutellarein from B. orellana and 3,5-dicaffeoylquinic acid from I. batatas, respectively, as potent inhibitors.
Zhong Xi Yi Jie He Za Zhi 1987 Jan;7(1):18-20, 4
Chrysanthemum morifolium in the treatment of hypertension[Article in Chinese]